If you’re going to tune into FOX tonight expecting a brand-new episode of Best Medicine, you might be wondering where Dr. Martin Best and the eccentric residents of Port Wenn went. The hit medical comedy-drama is currently airing Season 2 in its regular Tuesday night time slot, but your evening viewing plans are going to look a little different this week.
If you are looking for answers about tonight’s lineup, here is everything you need to know about why Best Medicine is missing and exactly when Season 2 will resume.
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Is Best Medicine on tonight?
No! Best Medicine is taking the week off, and there will be no new episode on Tuesday, Oct. 27.
Why is Best Medicine not on tonight?
Best Medicine is taking a temporary one-week timeout due to major live sports coverage. FOX is preempting its regular Tuesday night lineup to broadcast live coverage of the 2026 World Series.
Because the network holds exclusive broadcast rights for the Fall Classic — featuring a championship showdown between the Milwaukee Brewers and the Tampa Bay Rays — primetime programming blocks are entirely cleared to make room for Game 4. While baseball fans get a thrilling night of postseason action, fans of the medical series will need to press pause on their visit to the coast for just one week.
Related: FOX Is Making Major, Unexpected Shakeup to Its Iconic Sunday Night Lineup This Fall
When is Best Medicine on next?
The good news for fans of Josh Charles’ brilliant but abrasive small-town doctor is that the hiatus is short-lived. Best Medicine has not been canceled, and new episodes will return very soon. Mark your calendars: Season 2 picks right back up on Tuesday, Nov. 3, 2026, at its usual time of 8:00 p.m. ET/PT on Fox, with an all-new episode titled “Can’t Stop the Healing.”
What is airing on FOX instead tonight?
For viewers sticking with FOX tonight, the network’s primetime schedule is entirely dedicated to the World Series. Once the World Series concludes and November sweeps get underway, FOX’s regular Tuesday night schedule, featuring Best Medicine, will resume its normal weekly rhythm.
Related: FOX Finally Announces 2027 Premiere Date for New ‘Baywatch’ Reboot — With 1 Original Star Returning

